DGV431AB

Pseudophakia

ICD-10 Diagnosis Code:

Z96.1 — Presence of intraocular lens


Title

Lens Replaced by Other Means 


Category

Organ Or Tissue Replaced By Other Means (1)


Description

Pseudophakia is the term used to describe the replacement of a partial or complete opacity on or in the lens or capsule of one or both eyes with an artificial one.

Pseudophakia is the term used to describe the replacement of a partial or complete opacity on or in the lens or capsule of one or both eyes with an artificial one. Aaphakia_Pseudophak

Structural Damage to the Eye

  • Acquired loss of endothelial cells secondary to intraocular lens implant surgery
  • Cystoid macular edema can result from intraocular lens implant surgery 


Functional Damage to the Eye

  • Secondary cataracts can form on the intraocular lens 
  • Blurred vision due to secondary cataracts on the intraocular lens 
  • Corneal edema secondary to loss of endothelial cells after intraocular lens implant surgery

The main goal of the diagnostic evaluation in a patient with pseudophakia is to accomplish the following:

  • Determine if the intraocular lens is centered
  • Assess if secondary opacities are present
  • Determine if iatrogenic endotheliopathy has occurred
  • Evaluate the macula with OCT technology to determine if postoperative vitreoretinal pathology is present
  • Determine a treatment plan


Patient History

Patients will present with any of the following signs and symptoms:

  • No visual complaints
  • Blurred and/or distorted vision
  • Difficulty seeing in bright light


External Ocular Examination with Biomicroscopy

DGV431Pic01 Clinical Appearance of the Posterior Chamber

  • Pseudophakia
  • Posterior chamber intraocular lens
  • Clear posterior capsule
  • Centered introcular lens
Decentered IOL Clinical Appearance of the Posterior Chamber

  • Pseudophakia
  • Posterior chamber intraocular lens
  • Mild posterior capsule opacity
  • Slightly decenteredintraocular lens (superotemporally)
1a Clinical Appearance of the Posterior Chamber

  • Pseudophakia
  • Posterior chamber intraocular lens
  • Mild posterior capsule opacity
  • Slightly decenteredintraocular lens (superotemporally)
Sectoral Iris Atrophy Clinical Appearance of the Anterior Chamber

  • Pseudophakia
  • Anterior chamber intraocular lens
  • Sectoral iris atrophy secondary to intraocular lens

DIAGNOSTIC TESTS

External Ocular Photography

  • Document the severity of any secondary opacities
  • Document the progress or lack of progress of the opacities
  • Help determine a treatment plan

Pseudophakia

  • Posterior chamber intraocular lens
  • Severe clouding of the posterior capsule
  • Clear cornea
  • Normal corneal endothelium

 

Specular Endothelial Microscopy

  • Earlier and more accurate diagnosis of iatrogenic endotheliopathy
  • To evaluate unexplained loss of visual acuity after surgery
  • Document the progress or lack of progress of a corneal endotheliopathy
  • To help plan a treatment program
  • To document the delivery of medical treatment
  • To document the response to treatment
DGV431Pic08 Konan Specular Microscope

  • Visualize and analyze the corneal endothelium
  • Specular microscope captures the image reflected from the optical interface between the corneal endothelium and the acqeous humor
  • Instrument uses computer-assisted morphometry to analyze the size, shape and population of endothelial cells
Specular Microscopy — Three weeks Pre-OP

  • Normal rate of polymegethism in both eyes
  • No pleomorphism in both eyes
  • Normal thickness in both eyes
  • No corneal guttata in both eyes
  • Normal cell density in both eyes
  • Visual acuity = 20/50 in the right eye
DGV431Pic06a
Pseudophakia — Two weeks Post-OP in the right eye

  • Posterior chamber IOL
  • Clear posteror capsule
  • Centered IOL
  • Cloudy cornea indicates postoperative corneal edema
  • Cataract surgery generally results in a 4-10% loss of endothelial cells
  • Probable iatrogenic corneal endotheliopathy
  • Visual acuity = 20/40 in the right eye

 

DGV431Pic03
Specular Microscopy — Two weeks Post-OP

  • Iatrogenic corneal endotheliopathy in the right eye
  • Abnormal rate of polymegethism in the right eye
  • Presence of pleomorphism in the right eye
  • Corneal guttata in the right eye
  • Decrease endothelial cell density in the right eye
  • Visual acuity = 20/40 in the right eye
DGV431Pic07a

Retinal Laser Scan

  • Earlier and more acurate diagnosis of retinal disease
  • To evaluate unexplained loss of visual acuity after surgery
  • Document the progress or lack of progress of vitreomacular traction syndrome
  • Help plan a treatment program
  • To document the delivery of medical treatment
  • Document the response to treatment
  • Measure the effectiveness of therapy
  • Determine the need for ongoing therapy
1-page-001a Optical Coherence Technology — Three weeks Post-OP

  • Normal foveal architecture
  • Incomplete posterior vitreous detachment
  • Vitreous mebrane adhesion is present at the macula
  • No vitreomacular traction
2-page-001a (1) Optical Coherence Technology — Four months Post-OP

  • Normal foveal architecture
  • Incomplete posterior vitreous detachment
  • Vitreous membrane adhesions present at the macula
  • Vitreomacular traction is present
  • Chronic cystoid macular edema secondary to vitreomacular traction
  • Visual acuity = 20/50 right eye

There is no classification system in place for pseudophakia.

Optical Treatment

  • Prescription eyeglasses
  • Prescription contacts

Surgical Treatment
  • YAG laser capsulotomy
  • Refractice surgery for uncorrected postoperative refractive error 

1.  Graham R.  Aphakic and Pseudophakic Glaucoma.  2 Sept 2014. http://emedicine.medscape.com/article/1207170-overview.  Last accessed November 16, 2014.
2.  Prevalence of Cataract and Pseudophakia/Aphakia Among Adults in the United States.   Arch Ophthalmol. 2004;122(4):487-494.  http://archopht.jamanetwork.com/article.aspx?articleid=416230.  Last accessed November 16, 2014.

V43.1
Lens replaced by other means

92025
Corneal topography

92015
Refraction

92136
Ophthalmic biometry by A-scan with intraocular lens power calculation

92286
Specular endothelial microscopy

Occurrence

The prevalence of pseudophakia is linked to the number of senile cataracts.

  •  Senile cataracts are found in almost 66% of the population over 75 years old
  •  The prevalence is also linked to the number of congenial disorders that require cataract extraction


Distribution

  • No preference for males or females


Risk Factors

  • Age
  • Trauma
  • Congenital factors causing lens to be remove at a young age